1. (

• concern ,
• worry ,
• headache ,
• vexation

) something or someone that causes anxiety; a source of unhappiness; "New York traffic is a constant concern"; "it's a major worry" ;

2. (

• headache ,
• head_ache ,
• cephalalgia

) pain in the head caused by dilation of cerebral arteries or muscle contractions or a reaction to drugs ;