1. (

• substitute ,
• replace ,
• interchange ,
• exchange ,

) put in the place of another; switch seemingly equivalent items; "the con artist replaced the original with a fake Rembrandt"; "substitute regular milk for fat-free milk"; "synonyms can be interchanged without a changing the context's meaning" ;

2. (

• exchange ,
• change ,
• interchange

) give to, and receive from, one another; "Would you change places with me?"; "We have been exchanging letters for a year" ;

3. (

• counterchange ,
• transpose ,
• interchange ,

) cause to change places; "interchange this screw for one of a smaller size" ;

4. (

• interchange ,
• tack ,
• switch ,
• alternate ,
• flip ,
• flip-flop

) reverse (a direction, attitude, or course of action) ;