1. (

• irritation ,
• annoyance ,
• vexation ,
• botheration

) the psychological state of being irritated or annoyed ;

2. (

• pique ,
• temper ,
• irritation ,

) a sudden outburst of anger; "his temper sparked like damp firewood" ;

3. (

• irritation ,

) (pathology) abnormal sensitivity to stimulation; "any food produced irritation of the stomach" ;

4. (

• excitation ,
• innervation ,
• irritation ,

) the neural or electrical arousal of an organ or muscle or gland ;

5. (

• discomfort ,
• soreness ,
• irritation

) an uncomfortable feeling of mental painfulness or distress ;

6. (

• aggravation ,
• irritation ,
• provocation

) unfriendly behavior that causes anger or resentment ;

7. (

• annoyance ,
• annoying ,
• irritation ,
• vexation

) the act of troubling or annoying someone ;